Download the latest version from https://github.com/Minerx117/NemosMiner/releases
Extract the zip file
Run NemosMiner.bat

Set Wallet Address to your bitcoin address
Set Worker Name to a name for this machine - all your workers must have unique names
Set MPH UserName to your username on MiningPoolHub
Set MPH API Key to your MiningPoolHub API Key

You can change the other settings as desired. See the github page for full details.

Switch to the monitoring tab
Set server to https://nemosminer.com/
If this is your first worker: Click Generate New User ID
Otherwise: Copy and paste your exiting user ID into the box.
Check Report to server if you want to send status reports for this worker. You might leave this unchecked if you run the software on a machine you don't normally mine on.
Check Show other workers to retrieve the status of all your workers and show in the GUI. You might leave this unchecked on machines that run headless and don't need to show anything.
Click Save Config